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Proton extrusion during oxidative burst in microglia exacerbates pathological acidosis following traumatic brain injury

Acidosis is among the least studied secondary injury mechanisms associated with neurotrauma. Acute decreases in brain pH correlate with poor long‐term outcome in patients with traumatic brain injury (TBI), however, the temporal dynamics and underlying mechanisms are unclear. As key drivers of neuroi...

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Detalles Bibliográficos
Autores principales: Ritzel, Rodney M., He, Junyun, Li, Yun, Cao, Tuoxin, Khan, Niaz, Shim, Bosung, Sabirzhanov, Boris, Aubrecht, Taryn, Stoica, Bogdan A., Faden, Alan I., Wu, Long‐Jun, Wu, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819364/
https://www.ncbi.nlm.nih.gov/pubmed/33090575
http://dx.doi.org/10.1002/glia.23926