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The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells

BACKGROUND: Immunotherapy has been shown to be a promising strategy against human cancers. A better understanding of the immune regulation in hepatocellular carcinoma (HCC) could help the development of immunotherapy against HCC. The epidermal growth factor receptor (EGFR) signaling is frequently ac...

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Detalles Bibliográficos
Autores principales: Liu, Zongcai, Ning, Fen, Cai, Yanna, Sheng, Huiying, Zheng, Ruidan, Yin, Xi, Lu, Zhikun, Su, Ling, Chen, Xiaodan, Zeng, Chunhua, Wang, Haifang, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819566/
https://www.ncbi.nlm.nih.gov/pubmed/34236149
http://dx.doi.org/10.1002/cac2.12117