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Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses
The eponymous member of the interferon regulatory factor (IRF) family, IRF1, was originally identified as a nuclear factor that binds and activates the promoters of type I interferon genes. However, subsequent studies using genetic knockouts or RNAi-mediated depletion of IRF1 provide a much broader...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819612/ https://www.ncbi.nlm.nih.gov/pubmed/33476326 http://dx.doi.org/10.1371/journal.ppat.1009220 |