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Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses

The eponymous member of the interferon regulatory factor (IRF) family, IRF1, was originally identified as a nuclear factor that binds and activates the promoters of type I interferon genes. However, subsequent studies using genetic knockouts or RNAi-mediated depletion of IRF1 provide a much broader...

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Detalles Bibliográficos
Autores principales:	Feng, Hui, Zhang, Yi-Bing, Gui, Jian-Fang, Lemon, Stanley M., Yamane, Daisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819612/ https://www.ncbi.nlm.nih.gov/pubmed/33476326 http://dx.doi.org/10.1371/journal.ppat.1009220

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