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Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats

PURPOSE: To investigate the therapeutic benefits of Hydroxysafflor yellow A (HSYA) on blood-brain barrier (BBB) vulnerability after traumatic brain injury (TBI) and identify its potential action of mechanisms on TBIinduced injuries. METHODS: The rat TBI model was performed by using a controlled cort...

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Detalles Bibliográficos
Autores principales: Xu, Jianjun, Zhan, Tian, Zheng, Wan, Huang, Yun-Ke, Chen, Ken, Zhang, Xian-Hua, Ren, Ping, Huang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819693/
https://www.ncbi.nlm.nih.gov/pubmed/33503215
http://dx.doi.org/10.1590/ACB351202