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Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages

In this work, we have explored natural unmodified low- and high-density lipoproteins (LDL and HDL, respectively) as selective delivery vectors in colorectal cancer therapy. We show in vitro in cultured cells and in vivo (NanoSPECT/CT) in the CT-26 mice colorectal cancer model that LDLs are mainly ta...

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Detalles Bibliográficos
Autores principales: Hadi, Tarik, Ramseyer, Christophe, Gautier, Thomas, Bellaye, Pierre-Simon, Lopez, Tatiana, Schmitt, Antonin, Foley, Sarah, Yesylevskyy, Semen, Minervini, Thibault, Douhard, Romain, Dondaine, Lucile, Proukhnitzky, Lil, Messaoudi, Samir, Wendremaire, Maeva, Moreau, Mathieu, Neiers, Fabrice, Collin, Bertrand, Denat, Franck, Lagrost, Laurent, Garrido, Carmen, Lirussi, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819744/
https://www.ncbi.nlm.nih.gov/pubmed/33252359
http://dx.doi.org/10.1172/jci.insight.140280