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Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages
In this work, we have explored natural unmodified low- and high-density lipoproteins (LDL and HDL, respectively) as selective delivery vectors in colorectal cancer therapy. We show in vitro in cultured cells and in vivo (NanoSPECT/CT) in the CT-26 mice colorectal cancer model that LDLs are mainly ta...
Autores principales: | Hadi, Tarik, Ramseyer, Christophe, Gautier, Thomas, Bellaye, Pierre-Simon, Lopez, Tatiana, Schmitt, Antonin, Foley, Sarah, Yesylevskyy, Semen, Minervini, Thibault, Douhard, Romain, Dondaine, Lucile, Proukhnitzky, Lil, Messaoudi, Samir, Wendremaire, Maeva, Moreau, Mathieu, Neiers, Fabrice, Collin, Bertrand, Denat, Franck, Lagrost, Laurent, Garrido, Carmen, Lirussi, Frederic |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819744/ https://www.ncbi.nlm.nih.gov/pubmed/33252359 http://dx.doi.org/10.1172/jci.insight.140280 |
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