Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age

Cardiac fibrosis is a pathophysiologic hallmark of the aging heart, but little is known about how fibroblast proliferation and transcriptional programs change throughout the life span of the organism. Using EdU pulse labeling, we demonstrated that more than 50% of cardiac fibroblasts were actively p...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Rimao, Ma, Feiyang, Tosevska, Anela, Farrell, Colin, Pellegrini, Matteo, Deb, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819745/
https://www.ncbi.nlm.nih.gov/pubmed/33180747
http://dx.doi.org/10.1172/jci.insight.140628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819745/
https://www.ncbi.nlm.nih.gov/pubmed/33180747
http://dx.doi.org/10.1172/jci.insight.140628

Ejemplares similares