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Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice

Alveolar macrophages (AMs) are differentially regulated by human surfactant protein-A1 (SP-A1) or SP-A2. However, AMs are very heterogeneous and differences are difficult to characterize in intact cells. Using the Toponome Imaging System (TIS), an imaging technique that uses sequential immunostainin...

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Detalles Bibliográficos
Autores principales: Phelps, David S., Chinchilli, Vernon M., Weisz, Judith, Yang, Lili, Shearer, Debra, Zhang, Xuesheng, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819750/
https://www.ncbi.nlm.nih.gov/pubmed/33141765
http://dx.doi.org/10.1172/jci.insight.141410