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Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling
Genetic engineering of induced pluripotent stem cells (iPSCs) holds great promise for gene and cell therapy as well as drug discovery. However, there are potential concerns regarding the safety and control of gene expression using conventional vectors such as viruses and plasmids. Although human art...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819819/ https://www.ncbi.nlm.nih.gov/pubmed/33552683 http://dx.doi.org/10.1016/j.omtn.2020.12.012 |