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Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling

Genetic engineering of induced pluripotent stem cells (iPSCs) holds great promise for gene and cell therapy as well as drug discovery. However, there are potential concerns regarding the safety and control of gene expression using conventional vectors such as viruses and plasmids. Although human art...

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Detalles Bibliográficos
Autores principales:	Kazuki, Yasuhiro, Uno, Narumi, Abe, Satoshi, Kajitani, Naoyo, Kazuki, Kanako, Yakura, Yuwna, Sawada, Chiaki, Takata, Shuta, Sugawara, Masaki, Nagashima, Yuichi, Okada, Akane, Hiratsuka, Masaharu, Osaki, Mitsuhiko, Ferrari, Giulia, Tedesco, Francesco Saverio, Nishikawa, Satoshi, Fukumoto, Ken, Takayanagi, Shin-ichiro, Kunisato, Atsushi, Kaneko, Shin, Oshimura, Mitsuo, Tomizuka, Kazuma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819819/ https://www.ncbi.nlm.nih.gov/pubmed/33552683 http://dx.doi.org/10.1016/j.omtn.2020.12.012

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