Modulation of TASK-1/3 channels at the hypoglossal motoneuron pool and effects on tongue motor output and responses to excitatory inputs in vivo: implications for strategies for obstructive sleep apnea pharmacotherapy

Obstructive sleep apnea (OSA) occurs exclusively during sleep due to reduced tongue motor activity. Withdrawal of excitatory inputs to the hypoglossal motor nucleus (HMN) from wake to sleep contributes to this reduced activity. Several awake–active neurotransmitters with inputs to the HMN (e.g. sero...

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Detalles Bibliográficos
Autores principales: Gurges, Patrick, Liu, Hattie, Horner, Richard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Basic Science of Sleep and Circadian Rhythms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819847/
https://www.ncbi.nlm.nih.gov/pubmed/32745213
http://dx.doi.org/10.1093/sleep/zsaa144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819847/
https://www.ncbi.nlm.nih.gov/pubmed/32745213
http://dx.doi.org/10.1093/sleep/zsaa144

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