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Epigenetic modification and a role for the E3 ligase RNF40 in cancer development and metastasis

RNF40 (OMIM: 607700) is a really interesting new gene (RING) finger E3 ubiquitin ligase containing multiple coiled-coil domains and a C-terminal RING finger motif, which engage in protein–DNA and protein–protein interactions. RNF40 encodes a polypeptide of 1001 amino acids with a predicted molecular...

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Detalles Bibliográficos
Autores principales: Fu, Junjiang, Liao, Li, Balaji, Kyathegowdanadoddi Srinivasa, Wei, Chunli, Kim, Jaehoon, Peng, Jiangzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819849/
https://www.ncbi.nlm.nih.gov/pubmed/33199825
http://dx.doi.org/10.1038/s41388-020-01556-w