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Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung

Acute lung injury (ALI) is an important cause of morbidity and mortality after viral infections, including influenza A virus H1N1, SARS-CoV, MERS-CoV, and SARS-CoV-2. The angiotensin I converting enzyme 2 (ACE2) is a key host membrane-bound protein that modulates ALI induced by viral infection, pulm...

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Detalles Bibliográficos
Autores principales: Xu, Fuyi, Gao, Jun, Bergmann, Silke, Sims, Amy C., Ashbrook, David G., Baric, Ralph S., Cui, Yan, Jonsson, Colleen B., Li, Kui, Williams, Robert W., Schughart, Klaus, Lu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819859/
https://www.ncbi.nlm.nih.gov/pubmed/33488611
http://dx.doi.org/10.3389/fimmu.2020.607314