Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery

In this study, we integrate the outcomes of co-expression network analysis with the human interactome network to predict novel putative disease genes and modules. We first apply the SWItch Miner (SWIM) methodology, which predicts important (switch) genes within the co-expression network that regulat...

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Detalles Bibliográficos
Autores principales: Paci, Paola, Fiscon, Giulia, Conte, Federica, Wang, Rui-Sheng, Farina, Lorenzo, Loscalzo, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819998/
https://www.ncbi.nlm.nih.gov/pubmed/33479222
http://dx.doi.org/10.1038/s41540-020-00168-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819998/
https://www.ncbi.nlm.nih.gov/pubmed/33479222
http://dx.doi.org/10.1038/s41540-020-00168-0

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