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Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery
In this study, we integrate the outcomes of co-expression network analysis with the human interactome network to predict novel putative disease genes and modules. We first apply the SWItch Miner (SWIM) methodology, which predicts important (switch) genes within the co-expression network that regulat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819998/ https://www.ncbi.nlm.nih.gov/pubmed/33479222 http://dx.doi.org/10.1038/s41540-020-00168-0 |