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UTX/KDM6A deletion promotes the recovery of spinal cord injury by epigenetically triggering intrinsic neural regeneration

Interrupted axons that fail to regenerate mainly cause poor recovery after spinal cord injury (SCI). How neurons epigenetically respond to injury determines the intrinsic growth ability of axons. However, the mechanism underlying epigenetic regulation of axonal regeneration post-SCI remains largely...

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Detalles Bibliográficos
Autores principales: Guo, Zhu, Li, Chengjun, Cao, Yong, Qin, Tian, Jiang, Liyuan, Xu, Yan, Li, Miao, Luo, Zixiang, Hu, Jianzhong, Lu, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820127/
https://www.ncbi.nlm.nih.gov/pubmed/33553483
http://dx.doi.org/10.1016/j.omtm.2020.12.004