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Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

Pattern recognition receptors (PRRs) are germline-encoded host sensors of the innate immune system. Some human cancer cells have been reported to express PRRs. However, nucleic acid sensors in human cancers have not been studied in detail. Therefore, we systematically analyzed the expression, molecu...

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Detalles Bibliográficos
Autores principales: Qiao, Yuan, Zhu, Shan, Deng, Shuanglin, Zou, Shan-Shan, Gao, Bao, Zang, Guoxia, Wu, Jing, Jiang, Yuxue, Liu, Yong-Jun, Chen, Jingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820189/
https://www.ncbi.nlm.nih.gov/pubmed/33490069
http://dx.doi.org/10.3389/fcell.2020.606001