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Deficiency of the RIβ subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats

The RIβ subunit of cAMP-dependent protein kinase (PKA), encoded by Prkar1b, is a neuronal isoform of the type I regulatory subunit of PKA. Mice lacking the RIβ subunit exhibit normal long-term potentiation (LTP) in the Schaffer collateral pathway of the hippocampus and normal behavior in the open-fi...

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Detalles Bibliográficos
Autores principales: Hoang Trung, Hieu, Yoshihara, Toru, Nakao, Akito, Hayashida, Katsumi, Hirata, Yoshiki, Shirasuna, Koumei, Kuwamura, Mitsuru, Nakagawa, Yuki, Kaneko, Takehito, Mori, Yasuo, Asano, Masahide, Kuramoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820254/
https://www.ncbi.nlm.nih.gov/pubmed/33479380
http://dx.doi.org/10.1038/s41598-021-81515-x