A new mouse model for retinal degeneration due to Fam161a deficiency

FAM161A mutations are the most common cause of inherited retinal degenerations in Israel. We generated a knockout (KO) mouse model, Fam161a(tm1b/tm1b), lacking the major exon #3 which was replaced by a construct that include LacZ under the expression of the Fam161a promoter. LacZ staining was eviden...

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Detalles Bibliográficos
Autores principales: Beryozkin, Avigail, Matsevich, Chen, Obolensky, Alexey, Kostic, Corinne, Arsenijevic, Yvan, Wolfrum, Uwe, Banin, Eyal, Sharon, Dror
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820261/
https://www.ncbi.nlm.nih.gov/pubmed/33479377
http://dx.doi.org/10.1038/s41598-021-81414-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820261/
https://www.ncbi.nlm.nih.gov/pubmed/33479377
http://dx.doi.org/10.1038/s41598-021-81414-1

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