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An epitope-based malaria vaccine targeting the junctional region of circumsporozoite protein

A malaria vaccine that elicits long-lasting protection and is suitable for use in endemic areas remains urgently needed. Here, we assessed the immunogenicity and prophylactic efficacy of a vaccine targeting a recently described epitope on the major surface antigen on Plasmodium falciparum sporozoite...

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Detalles Bibliográficos
Autores principales: Jelínková, Lucie, Jhun, Hugo, Eaton, Allison, Petrovsky, Nikolai, Zavala, Fidel, Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820318/
https://www.ncbi.nlm.nih.gov/pubmed/33479242
http://dx.doi.org/10.1038/s41541-020-00274-4