Molecular mechanism underlying the selective attack of trehalose lipids on cancer cells as revealed by coarse-grained molecular dynamics simulations

The present study indicated that the mixed lipid bilayer of dimyristoylphosphatidylcholine (DMPC) and trehalosemonomyristate (TreC14) interacted strongly with the plasma membrane of cancer cells, and not that of normal cells, when the composition of TreC14 was 70%, as revealed by coarse-grained mole...

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Detalles Bibliográficos
Autores principales: Hirano, Ryosuke, Kagamiya, Takashi, Matsumoto, Yoko, Furuta, Tadaomi, Sakurai, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820381/
https://www.ncbi.nlm.nih.gov/pubmed/33521337
http://dx.doi.org/10.1016/j.bbrep.2021.100913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820381/
https://www.ncbi.nlm.nih.gov/pubmed/33521337
http://dx.doi.org/10.1016/j.bbrep.2021.100913

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