Ex vivo culture of intact human patient derived pancreatic tumour tissue

The poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is attributed to the highly fibrotic stroma and complex multi-cellular microenvironment that is difficult to fully recapitulate in pre-clinical models. To fast-track translation of therapies and to inform personalised medicine, we aimed t...

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Detalles Bibliográficos
Autores principales: Kokkinos, John, Sharbeen, George, Haghighi, Koroush S., Ignacio, Rosa Mistica C., Kopecky, Chantal, Gonzales-Aloy, Estrella, Youkhana, Janet, Timpson, Paul, Pereira, Brooke A., Ritchie, Shona, Pandzic, Elvis, Boyer, Cyrille, Davis, Thomas P., Butler, Lisa M., Goldstein, David, McCarroll, Joshua A., Phillips, Phoebe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820421/
https://www.ncbi.nlm.nih.gov/pubmed/33479301
http://dx.doi.org/10.1038/s41598-021-81299-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820421/
https://www.ncbi.nlm.nih.gov/pubmed/33479301
http://dx.doi.org/10.1038/s41598-021-81299-0

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