Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres

To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms to prevent telomere shortening. ~85% of cancers circumvent telomeric attrition by re-expressing telomerase, while the remaining ~15% of cancers induce alternative lengthening of telomeres (ALT), which reli...

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Detalles Bibliográficos
Autores principales: Lippert, Timothy P., Marzec, Paulina, Idilli, Aurora I., Sarek, Grzegorz, Vancevska, Aleksandra, Bower, Mark, Farrell, Paul J., Ojala, Päivi M., Feldhahn, Niklas, Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820467/
https://www.ncbi.nlm.nih.gov/pubmed/33479235
http://dx.doi.org/10.1038/s41467-020-20819-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820467/
https://www.ncbi.nlm.nih.gov/pubmed/33479235
http://dx.doi.org/10.1038/s41467-020-20819-4

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