Cellular reprogramming with multigene activation by the delivery of CRISPR/dCas9 ribonucleoproteins via magnetic peptide-imprinted chitosan nanoparticles

Induced pluripotent stem cells are usually derived by reprogramming transcription factors (OSKM), such as octamer-binding transcription factor 4 (OCT4), (sex determining region Y)-box 2 (SOX2), Krüppel-like factor 4 (KLF4), and cellular proto-oncogene (c-Myc). However, the genomic integration of tra...

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Detalles Bibliográficos
Autores principales: Lee, Mei-Hwa, Lin, Cheng-Chih, Thomas, James L., Li, Jin-An, Lin, Hung-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820544/
https://www.ncbi.nlm.nih.gov/pubmed/33521619
http://dx.doi.org/10.1016/j.mtbio.2020.100091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820544/
https://www.ncbi.nlm.nih.gov/pubmed/33521619
http://dx.doi.org/10.1016/j.mtbio.2020.100091

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