Cargando…

Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate

Bile acids are metabolites of cholesterol that facilitate lipid digestion and absorption in the small bowel. Bile acids work as agonists of receptors to regulate their own metabolism. Bile acids also regulate other biological systems such as sugar metabolism, intestinal multidrug resistance, and ada...

Descripción completa

Detalles Bibliográficos
Autores principales: Ota, Tomoki, Senoo, Akinobu, Shirakawa, Masumi, Nonaka, Hiroshi, Saito, Yutaro, Ito, Sho, Ueno, Go, Nagatoishi, Satoru, Tsumoto, Kouhei, Sando, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820547/
https://www.ncbi.nlm.nih.gov/pubmed/33521601
http://dx.doi.org/10.1016/j.isci.2021.102036