Cargando…
Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate
Bile acids are metabolites of cholesterol that facilitate lipid digestion and absorption in the small bowel. Bile acids work as agonists of receptors to regulate their own metabolism. Bile acids also regulate other biological systems such as sugar metabolism, intestinal multidrug resistance, and ada...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820547/ https://www.ncbi.nlm.nih.gov/pubmed/33521601 http://dx.doi.org/10.1016/j.isci.2021.102036 |