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Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins

Chronic inflammation during many diseases is associated with bone loss. While interferons (IFNs) are often inhibitory to osteoclast formation, the complex role that IFN and interferon-stimulated genes (ISGs) play in osteoimmunology during inflammatory diseases is still poorly understood. We show tha...

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Detalles Bibliográficos
Autores principales: Place, David E., Malireddi, R. K. Subbarao, Kim, Jieun, Vogel, Peter, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820603/
https://www.ncbi.nlm.nih.gov/pubmed/33479228
http://dx.doi.org/10.1038/s41467-020-20807-8