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Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
Chronic inflammation during many diseases is associated with bone loss. While interferons (IFNs) are often inhibitory to osteoclast formation, the complex role that IFN and interferon-stimulated genes (ISGs) play in osteoimmunology during inflammatory diseases is still poorly understood. We show tha...
Autores principales: | Place, David E., Malireddi, R. K. Subbarao, Kim, Jieun, Vogel, Peter, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820603/ https://www.ncbi.nlm.nih.gov/pubmed/33479228 http://dx.doi.org/10.1038/s41467-020-20807-8 |
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