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Comparative Genomic Analysis of Mycobacteriaceae Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the Mycobacterium tuberculosis Complex

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are conserved genetic elements in many prokaryotes, including Mycobacterium tuberculosis, the causative agent of tuberculosis. Although knowledge of CRISPR locus variability has been utilized in M. t...

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Detalles Bibliográficos
Autores principales: Singh, Anoop, Gaur, Mohita, Sharma, Vishal, Khanna, Palak, Bothra, Ankur, Bhaduri, Asani, Mondal, Anupam Kumar, Dash, Debasis, Singh, Yogendra, Misra, Richa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820667/
https://www.ncbi.nlm.nih.gov/pubmed/33468705
http://dx.doi.org/10.1128/mSystems.00934-20