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Grass Carp (Ctenopharyngodon idellus) NIMA-Related Kinase 6 Blocks dsRNA-Induced IFN I Response by Targeting IRF3

Accumulating evidence indicates that mammalian NIMA (never in mitosis, gene A)-related kinase 6 (NEK6) plays potential roles during the course of tumorigenesis, but little is known about NEK6 in lower vertebrates. Herein, we reported a mammalian ortholog of NEK6 in grass carp (Ctenopharyngodon idell...

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Detalles Bibliográficos
Autores principales: Xu, Xiaowen, Li, Meifeng, Deng, Zeyuan, Hu, Jihuan, Jiang, Zeyin, Liu, Yapeng, Chang, Kaile, Hu, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820699/
https://www.ncbi.nlm.nih.gov/pubmed/33488591
http://dx.doi.org/10.3389/fimmu.2020.597775