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A Simulation Study of the Role of Mechanical Stretch in Arrhythmogenesis during Cardiac Alternans

The deformation of the heart tissue due to the contraction can modulate the excitation, a phenomenon referred to as mechanoelectrical feedback (MEF), via stretch-activated channels. The effects of MEF on the electrophysiology at high pacing rates are shown to be proarrhythmic in general. However, mo...

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Detalles Bibliográficos
Autores principales: Hazim, Azzam, Belhamadia, Youssef, Dubljevic, Stevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820729/
https://www.ncbi.nlm.nih.gov/pubmed/33248131
http://dx.doi.org/10.1016/j.bpj.2020.11.018