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A Simulation Study of the Role of Mechanical Stretch in Arrhythmogenesis during Cardiac Alternans
The deformation of the heart tissue due to the contraction can modulate the excitation, a phenomenon referred to as mechanoelectrical feedback (MEF), via stretch-activated channels. The effects of MEF on the electrophysiology at high pacing rates are shown to be proarrhythmic in general. However, mo...
Autores principales: | Hazim, Azzam, Belhamadia, Youssef, Dubljevic, Stevan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820729/ https://www.ncbi.nlm.nih.gov/pubmed/33248131 http://dx.doi.org/10.1016/j.bpj.2020.11.018 |
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