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LAG3’s Enigmatic Mechanism of Action

LAG3 is an important immune checkpoint with relevance in cancer, infectious disease and autoimmunity. However, despite LAG3’s role in immune exhaustion and the great potential of LAG3 inhibition as treatment, much remains unknown about its biology, particularly its mechanism of action. This review d...

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Detalles Bibliográficos
Autores principales: Graydon, Colin G., Mohideen, Shifa, Fowke, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820757/
https://www.ncbi.nlm.nih.gov/pubmed/33488626
http://dx.doi.org/10.3389/fimmu.2020.615317