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The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development
BACKGROUND: Cryptophthalmos is characterized by congenital ocular dysplasia with eyelid malformation. The pathogenicity of mutations in genes encoding components of the FRAS1/FREM protein complex is well established, but the underlying pathomechanisms of this disease are still unclear. In the previo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820765/ https://www.ncbi.nlm.nih.gov/pubmed/33490088 http://dx.doi.org/10.3389/fcell.2020.625492 |