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The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development

BACKGROUND: Cryptophthalmos is characterized by congenital ocular dysplasia with eyelid malformation. The pathogenicity of mutations in genes encoding components of the FRAS1/FREM protein complex is well established, but the underlying pathomechanisms of this disease are still unclear. In the previo...

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Detalles Bibliográficos
Autores principales: Zhang, Xiayin, Wang, Ruixin, Wang, Ting, Zhang, Xulin, Dongye, Meimei, Wang, Dongni, Wang, Jinghui, Li, Wangting, Wu, Xiaohang, Lin, Duoru, Lin, Haotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820765/
https://www.ncbi.nlm.nih.gov/pubmed/33490088
http://dx.doi.org/10.3389/fcell.2020.625492