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Toward Therapeutic Targeting of Bone Marrow Leukemic Niche Protective Signals in B-Cell Acute Lymphoblastic Leukemia

B-cell acute lymphoblastic leukemia (B-ALL) represents the malignant counterpart of bone marrow (BM) differentiating B cells and occurs most frequently in children. While new combinations of chemotherapeutic agents have dramatically improved the prognosis for young patients, disease outcome remains...

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Detalles Bibliográficos
Autores principales: Delahaye, Marjorie C., Salem, Kaoutar-Insaf, Pelletier, Jeoffrey, Aurrand-Lions, Michel, Mancini, Stéphane J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820772/
https://www.ncbi.nlm.nih.gov/pubmed/33489914
http://dx.doi.org/10.3389/fonc.2020.606540