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PD-L1/PD-1 Pattern of Expression Within the Bone Marrow Immune Microenvironment in Smoldering Myeloma and Active Multiple Myeloma Patients

BACKGROUND: The PD-1/PD-L1 axis has recently emerged as an immune checkpoint that controls antitumor immune responses also in hematological malignancies. However, the use of anti-PD-L1/PD-1 antibodies in multiple myeloma (MM) patients still remains debated, at least in part because of discordant lit...

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Detalles Bibliográficos
Autores principales: Costa, Federica, Vescovini, Rosanna, Marchica, Valentina, Storti, Paola, Notarfranchi, Laura, Dalla Palma, Benedetta, Toscani, Denise, Burroughs-Garcia, Jessica, Catarozzo, Maria Teresa, Sammarelli, Gabriella, Giuliani, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820813/
https://www.ncbi.nlm.nih.gov/pubmed/33488620
http://dx.doi.org/10.3389/fimmu.2020.613007