Cargando…

SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references

Recent advances in single-cell RNA sequencing (scRNA-seq) enable characterization of transcriptomic profiles with single-cell resolution and circumvent averaging artifacts associated with traditional bulk RNA sequencing (RNA-seq) data. Here, we propose SCDC, a deconvolution method for bulk RNA-seq t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Meichen, Thennavan, Aatish, Urrutia, Eugene, Li, Yun, Perou, Charles M, Zou, Fei, Jiang, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820884/
https://www.ncbi.nlm.nih.gov/pubmed/31925417
http://dx.doi.org/10.1093/bib/bbz166