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An Efficient and Easy-to-Use Network-Based Integrative Method of Multi-Omics Data for Cancer Genes Discovery

Identifying personalized driver genes is essential for discovering critical biomarkers and developing effective personalized therapies of cancers. However, few methods consider weights for different types of mutations and efficiently distinguish driver genes over a larger number of passenger genes....

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Detalles Bibliográficos
Autores principales: Wei, Ting, Fa, Botao, Luo, Chengwen, Johnston, Luke, Zhang, Yue, Yu, Zhangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820902/
https://www.ncbi.nlm.nih.gov/pubmed/33488678
http://dx.doi.org/10.3389/fgene.2020.613033