Hirsutella Sinensis Fungus Regulates CD8(+) T Cell Exhaustion Through Involvement of T-Bet/Eomes in the Tumor Microenvironment

Background: Targeting exhausted T (Tex) cells is a promising strategy for anti-tumour treatment. Previously, we demonstrated that Hirsutella sinensis fungus (HSF) could significantly increase T cell infiltration and the effector T cell ratio in the tumor microenvironment, activating systemic immune...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Lu, Jin, Lushuai, Wu, Renjie, Liu, Xia, Zhu, Xinhai, Shou, Qiyang, Fu, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820905/
https://www.ncbi.nlm.nih.gov/pubmed/33488388
http://dx.doi.org/10.3389/fphar.2020.612620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820905/
https://www.ncbi.nlm.nih.gov/pubmed/33488388
http://dx.doi.org/10.3389/fphar.2020.612620

Ejemplares similares