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Hirsutella Sinensis Fungus Regulates CD8(+) T Cell Exhaustion Through Involvement of T-Bet/Eomes in the Tumor Microenvironment
Background: Targeting exhausted T (Tex) cells is a promising strategy for anti-tumour treatment. Previously, we demonstrated that Hirsutella sinensis fungus (HSF) could significantly increase T cell infiltration and the effector T cell ratio in the tumor microenvironment, activating systemic immune...
Autores principales: | Jin, Lu, Jin, Lushuai, Wu, Renjie, Liu, Xia, Zhu, Xinhai, Shou, Qiyang, Fu, Huiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820905/ https://www.ncbi.nlm.nih.gov/pubmed/33488388 http://dx.doi.org/10.3389/fphar.2020.612620 |
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