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Quantification of an Adverse Outcome Pathway Network by Bayesian Regression and Bayesian Network Modeling

The adverse outcome pathway (AOP) framework has gained international recognition as a systematic approach linking mechanistic processes to toxicity endpoints. Nevertheless, successful implementation into risk assessments is still limited by the lack of quantitative AOP models (qAOPs) and assessment...

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Detalles Bibliográficos
Autores principales: Moe, S Jannicke, Wolf, Raoul, Xie, Li, Landis, Wayne G, Kotamäki, Niina, Tollefsen, Knut Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7820971/
https://www.ncbi.nlm.nih.gov/pubmed/32965776
http://dx.doi.org/10.1002/ieam.4348