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Intranasal delivery of experimental compounds in orthotopic brain tumor mouse models

Effective therapeutics for malignant primary brain tumors, such as glioblastomas (GBMs), are urgently needed. To facilitate and expedite early-phase GBM therapeutic development, we describe a protocol that allows the intranasal delivery of experimental compounds in GBM orthotopic mouse models. Compo...

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Detalles Bibliográficos
Autores principales: Eyme, Katharina M., Carvalho, Litia, Badr, Christian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821034/
https://www.ncbi.nlm.nih.gov/pubmed/33532737
http://dx.doi.org/10.1016/j.xpro.2020.100290