Using Mutability Landscapes To Guide Enzyme Thermostabilization

Thermostabilizing enzymes while retaining their activity and enantioselectivity for applied biocatalysis is an important topic in protein engineering. Rational and computational design strategies as well as directed evolution have been used successfully to thermostabilize enzymes. Herein, we describ...

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Detalles Bibliográficos
Autores principales: Guo, Chao, Ni, Yan, Biewenga, Lieuwe, Pijning, Tjaard, Thunnissen, Andy‐Mark W. H., Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821111/
https://www.ncbi.nlm.nih.gov/pubmed/32790123
http://dx.doi.org/10.1002/cbic.202000442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821111/
https://www.ncbi.nlm.nih.gov/pubmed/32790123
http://dx.doi.org/10.1002/cbic.202000442

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