Pharmacogenetic studies of thiopurine methyltransferase genotype‐phenotype concordance and effect of methotrexate on thiopurine metabolism

The discovery and implementation of thiopurine methyltransferase (TPMT) pharmacogenetics has been a success story and has reduced the suffering from serious adverse reactions during thiopurine treatment of childhood leukaemia and inflammatory bowel disease. This MiniReview summarizes four studies in...

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Detalles Bibliográficos
Autores principales: Zimdahl Kahlin, Anna, Helander, Sara, Wennerstrand, Patricia, Vikingsson, Svante, Mårtensson, Lars‐Göran, Appell, Malin Lindqvist
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821157/
https://www.ncbi.nlm.nih.gov/pubmed/32865889
http://dx.doi.org/10.1111/bcpt.13483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821157/
https://www.ncbi.nlm.nih.gov/pubmed/32865889
http://dx.doi.org/10.1111/bcpt.13483

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