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Pharmacogenetic studies of thiopurine methyltransferase genotype‐phenotype concordance and effect of methotrexate on thiopurine metabolism
The discovery and implementation of thiopurine methyltransferase (TPMT) pharmacogenetics has been a success story and has reduced the suffering from serious adverse reactions during thiopurine treatment of childhood leukaemia and inflammatory bowel disease. This MiniReview summarizes four studies in...
Autores principales: | Zimdahl Kahlin, Anna, Helander, Sara, Wennerstrand, Patricia, Vikingsson, Svante, Mårtensson, Lars‐Göran, Appell, Malin Lindqvist |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821157/ https://www.ncbi.nlm.nih.gov/pubmed/32865889 http://dx.doi.org/10.1111/bcpt.13483 |
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