Combination Treatment With Metformin and Tacrolimus Improves Systemic Immune Cellular Homeostasis by Modulating Treg and Th17 Imbalance

We examined the effect of combination therapy with metformin and tacrolimus on immune parameters including T regulatory (Treg) and type 17 helper T (Th17) cells in vitro and in vivo in mice and in liver transplantation (LT) patients. T cell proliferation and subtypes after in vitro T cell activation...

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Detalles Bibliográficos
Autores principales: Lee, Soon Kyu, Park, Min-Jung, Jhun, Joo Yeon, Beak, Jin-Ah, Choi, Jeong Won, Rye, Jae-Yoon, Jang, Jeong Won, Bae, Si Hyun, Yoon, Seung Kew, Choi, Ho Joong, You, Young Kyoung, Cho, Mi-La, Choi, Jong Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821164/
https://www.ncbi.nlm.nih.gov/pubmed/33488583
http://dx.doi.org/10.3389/fimmu.2020.581728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821164/
https://www.ncbi.nlm.nih.gov/pubmed/33488583
http://dx.doi.org/10.3389/fimmu.2020.581728

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