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Novel phenolic antimicrobials enhanced activity of iminodiacetate prodrugs against biofilm and planktonic bacteria

Prodrugs are pharmacologically attenuated derivatives of drugs that undergo bioconversion into the active compound once reaching the targeted site, thereby maximizing their efficiency. This strategy has been implemented in pharmaceuticals to overcome obstacles related to absorption, distribution, an...

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Detalles Bibliográficos
Autores principales: Walsh, Danica J., Livinghouse, Tom, Durling, Greg M., Arnold, Adrienne D., Brasier, Whitney, Berry, Luke, Goeres, Darla M., Stewart, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821224/
https://www.ncbi.nlm.nih.gov/pubmed/32844569
http://dx.doi.org/10.1111/cbdd.13768