Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

BACKGROUND: The proprotein convertase subtilisin/kexin type 9 (PCSK9) has been implicated in the pathogenesis of inflammatory diseases. We sought to investigate the role of PCSK9 in the pathogenesis of Graves’ orbitopathy (GO) and whether it may be a legitimate target for treatment. METHODS: The PCS...

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Detalles Bibliográficos
Autores principales: Lee, Ga Eun, Kim, Jinjoo, Lee, Jihei Sara, Ko, JaeSang, Lee, Eun Jig, Yoon, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821242/
https://www.ncbi.nlm.nih.gov/pubmed/33488522
http://dx.doi.org/10.3389/fendo.2020.607144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821242/
https://www.ncbi.nlm.nih.gov/pubmed/33488522
http://dx.doi.org/10.3389/fendo.2020.607144

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