Asymmetric α‐Chlorination of β‐Keto Esters Using Hypervalent Iodine‐Based Cl‐Transfer Reagents in Combination with Cinchona Alkaloid Catalysts

We herein report an unprecedented strategy for the asymmetric α‐chlorination of β‐keto esters with hypervalent iodine‐based Cl‐transfer reagents using simple Cinchona alkaloid catalysts. Our investigations support an α‐chlorination mechanism where the Cinchona species serves as a nucleophilic cataly...

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Detalles Bibliográficos
Autores principales: Stockhammer, Lotte, Schörgenhumer, Johannes, Mairhofer, Christopher, Waser, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821243/
https://www.ncbi.nlm.nih.gov/pubmed/33519300
http://dx.doi.org/10.1002/ejoc.202001217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821243/
https://www.ncbi.nlm.nih.gov/pubmed/33519300
http://dx.doi.org/10.1002/ejoc.202001217

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