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In Lyl1 (−/−) mice, adipose stem cell vascular niche impairment leads to premature development of fat tissues

Lyl1 encodes a hematopoietic‐ and endothelial‐specific bHLH transcription factor. Lyl1‐deficient mice are viable, but they display mild hematopoietic and vascular defects. Specifically, LYL1 is required for the maturation and stabilization of blood vessel endothelial adherens junctions. Here, we rep...

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Detalles Bibliográficos
Autores principales: Hussain, Abid, Deleuze, Virginie, El Kebriti, Leila, Turali, Hulya, Pirot, Nelly, Glasson, Yaël, Mathieu, Danièle, Pinet, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821250/
https://www.ncbi.nlm.nih.gov/pubmed/33022858
http://dx.doi.org/10.1002/stem.3286